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Cancer Clinical Research Nurse II

  • Massachusetts, Boston

  • 03/24/2026

  • Contract

  • Active

Job Description:

  • Job Summary  
    The Clinical Research Nurse II (CRN II) reports directly to the Medical Director of the Cancer Clinical Trials Program and the Administrative Director in Hematology and Medical Oncology. This role is primarily responsible for performing clinical and patient-facing tasks for patients enrolled in clinical trials. The CRN II collaborates with providers to identify eligible patients, reviews consent forms, ensures compliance with study requirements, and provides clinical perspective to regulatory coordinators. The nurse will spend the majority of their time in clinic, following and evaluating 16–24 patients per week.

    Key Responsibilities
    1. Administrative
    2. Assist principal investigators with protocol review and development.
    3. Collaborate on quality assurance and development of protocol-specific materials.
    4. Research
    5. Recruit and register patients for clinical trials.
    6. Coordinate scheduling of labs, imaging, admissions, and clinic visits.
    7. Monitor test results and collaborate with research coordinators and disease group staff.
    8. Clinical
    9. Coordinate study enrollment, protocol treatment, and completion of study requirements.
    10. Collaborate with care coordination and primary nurses to ensure patient care needs are met.
    11. Provide protocol education to patients and families, adapting to cultural and age-specific needs.
    12. Order specimens, monitor test results, and administer medications as necessary.
    13. Document patient encounters and communicate findings to investigators and physicians.
    14. Provide protocol in-service training and serve as a resource to the healthcare team.
    15. Monitor patient safety and ensure compliance with regulatory standards.
    16. Maintain evidence-based clinical practice consistent with nursing policies and licensure requirements.
    17. Professional Development
    18. Identify areas for professional growth and set goals.
    19. Participate in professional organizations, committees, and training.
    20. Prepare reports, articles, and presentations for colleagues and the public.

    Required Qualifications
    1. Graduate of an accredited nursing program.
    2. Bachelor’s degree required.
    3. Licensed RN in the Commonwealth of Massachusetts.
    4. Current Basic Cardiac Life Support (BCLS) certification.
    5. 3–5 years of research or clinical research experience.

    Knowledge & Skills
    1. Proficiency in Microsoft Office (Word, Excel, PowerPoint, Outlook) and web browsers.
    2. Ability to input/analyze data and generate reports (REDCap experience preferred).
    3. Strong organizational, detail-oriented, and problem-solving skills.
    4. Knowledge of research regulations and compliance requirements, including Protection of Human Subjects.
    5. Ability to maintain confidentiality of sensitive information.
    6. Experience with grant writing, IRB submissions, data management, and study coordination preferred.
    7. Excellent communication skills (oral and written); bilingual/multilingual skills a plus.
    8. Cultural sensitivity and ability to work with diverse populations.

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