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Senior Python Developer

  • North Carolina, Durham

  • 06/29/2026

  • Contract

  • Active

Job Description:

  • Job Summary
    The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations, and system modernization. This role supports a core monolithic platform built with Python and Django while driving architectural improvements, mentoring engineers, and delivering scalable, high-quality software solutions. The ideal candidate has extensive experience with Python, Django, TypeScript, API development, and full-stack application engineering.

    Key Responsibilities
    • Design, develop, and maintain enterprise applications using Python and Django.
    • Enhance and support a core monolithic application responsible for processing and orchestration.
    • Design, develop, and maintain RESTful APIs and integration services for internal systems.
    • Build and enhance full-stack applications with a strong emphasis on backend development and TypeScript.
    • Develop and maintain integrations supporting enterprise platform functionality.
    • Perform system modernization, performance improvements, and platform stability enhancements.
    • Participate in architecture discussions and contribute to technical design decisions.
    • Troubleshoot production issues, perform root cause analysis, and implement permanent solutions.
    • Participate in production support and on-call rotations.
    • Collaborate with cross-functional teams including product, platform, and business stakeholders.
    • Mentor junior engineers and promote software engineering best practices.
    • Communicate technical concepts effectively with both technical and non-technical stakeholders.
    • Contribute to continuous improvement initiatives and engineering standards.

    Required Qualifications
    • 7+ years of professional software engineering experience.
    • Strong hands-on experience with Python development.
    • Strong experience developing enterprise applications using Django.
    • Full-stack development experience with a strong backend focus.
    • Extensive experience developing RESTful APIs and service-oriented architectures.
    • Strong experience with TypeScript for frontend and backend development.
    • Experience working with MySQL databases.
    • Strong knowledge of software architecture, system design, and application development best practices.
    • Strong analytical, debugging, troubleshooting, and problem-solving skills.
    • Excellent communication, collaboration, and mentoring skills.
    • Ability to independently solve complex technical problems and deliver scalable solutions.

    Preferred Qualifications
    • Experience in healthcare technology, clinical laboratory, or genomics environments.
    • Experience with AWS cloud services and cloud-native application development.
    • Experience with Docker, Kubernetes, or containerized application deployments.
    • Experience with Infrastructure as Code tools such as Terraform.
    • Experience designing and maintaining enterprise API platforms.
    • Familiarity with AI-assisted development tools such as Claude or Codex.

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